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  • Title: Monitored long-term treatment with ibopamine in patients suffering from severe congestive heart failure.
    Author: Avanzini Z, Bellogini GC, Brusoni B, Ciampani N, Dei Cas L, Gazzola U, Maggi GC, Mangiavacchi M, Metra M, Pinca L.
    Journal: Arzneimittelforschung; 1986 Feb; 36(2A):394-7. PubMed ID: 3707656.
    Abstract:
    50 patients with congestive heart failure underwent monitored long-term treatment aimed at evaluating the effect of ibopamine (SB-7505), the 3,4-diisobutyryl ester of N-methyldopamine, on their condition. Ibopamine was administered alone or in combination with traditional therapy mainly at a dose of 100 mg t.i.d. Clinical scores and NYHA (New York Heart Association) functional classes improved. Biochemical parameters showed no adverse modifications. Mild transient side-effects probably related to ibopamine occurred in two patients.
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