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  • Title: [Chronopharmacological characteristics of the action of dehydrocholic acid on bile formation].
    Author: Skakun NP, Davydovich OV.
    Journal: Farmakol Toksikol; 1986; 49(2):40-5. PubMed ID: 3709774.
    Abstract:
    Peculiarities of the liver response to dehydrocholic acid, conditioned by the time of its administration during the day and by the seasons of the year were revealed in experiments on random bred mature white rats. The dependence of this reaction on the time factor was manifested in all the main indicators of cholopoiesis--in the rate of bile secretion, synthesis and secretion of bile acids and bilirubin, cholesterol excretion.
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