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  • Title: Seven New Lobane Diterpenoids from the Soft Coral Lobophytum catalai.
    Author: Zhang J, Ma H, Jin S, Liu X, Li L, Liu Z, Li G, Li P.
    Journal: Mar Drugs; 2023 Mar 30; 21(4):. PubMed ID: 37103362.
    Abstract:
    Seven new lobane diterpenoids, namely, lobocatalens A-G (1-7), were isolated from the Xisha soft coral Lobophytum catalai. Their structures, including their absolute configurations, were elucidated via spectroscopic analysis, comparison with the literature data, QM-MNR, and TDDFT-ECD calculations. Among them, lobocatalen A (1) is a new lobane diterpenoid with an unusual ether linkage between C-14 and C-18. In addition, compound 7 showed moderate anti-inflammatory activity in the zebrafish models and cytotoxic activity against the K562 human cancer cell line.
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