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  • Title: A simple procedure for the purification of neutral salt soluble type I collagen from skin.
    Author: Speranza ML, Valentini G.
    Journal: Ital J Biochem; 1986; 35(1):42-8. PubMed ID: 3710766.
    Abstract:
    Intact monomeric type I collagen was purified from fetal bovine skin by a simple and time saving procedure. Saline precipitates of mixed skin collagens, in 4 M NaCl, were extracted with a limited volume of dilute acetic acid, taken in the proportion of 1 ml per g of original wet skin; NaCl in the precipitate was not removed by dialysis. The salt concentration in the extraction medium in the above conditions, selectively solubilized type I collagen.
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