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  • Title: A novel macrolide antibiotic, notonesomycin A.
    Author: Sasaki T, Furihata K, Shimazu A, Seto H, Iwata M, Watanabe T, Otake N.
    Journal: J Antibiot (Tokyo); 1986 Apr; 39(4):502-9. PubMed ID: 3710911.
    Abstract:
    Fermentation of Streptomyces aminophilus subsp. notonesogenes 647-AV1 produced a mixture of antifungal antibiotics. Notonesomycin A, the main component has been characterized as a new macrolide antibiotic containing a sulfate group, a malonate moiety, two deoxysugars and a 1,3,4-trisubstituted benzene system in the molecule. It was active against some fungi and Gram-positive bacteria in vitro and effective against the sheath blight disease of rice plant in a green house test.
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