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  • Title: [Pulmonitis and pulmonary fibrosis following radiotherapy of lymphogranulomatosis].
    Author: Kanaev SV, Kholin AV, Malinin AP.
    Journal: Vopr Onkol; 1986; 32(5):50-4. PubMed ID: 3716274.
    Abstract:
    Data on 314 cases of radiation and chemoradiation treatment for Hodgkin's disease were analysed. Pulmonitis was registered in 8.9 and paramediastinal fibrosis--in 37.6%. The incidence of pulmonitis did not vary with cumulative radiation effect (CRE) and time-dose-fraction (TDF) values computed for irradiation field area. A significant increase in the incidence of paramediastinal fibrosis was observed at CRE and TDF values exceeding 1,500 reu and 77 units, respectively. There was no relationship between the above pathology and treatment modality (60Co teletherapy and 25 MeV fast electrons).
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