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Title: Properties of anti-hairy cell serum. Author: Stuart AE, Dewar AE. Journal: Br J Haematol; 1979 Feb; 41(2):163-8. PubMed ID: 371661. Abstract: An antiserum was prepared in rabbits against hairy leukaemic cells. After absorption with human erythrocytes, thymus and liver powder, the serum was passed through immunoabsorbent columns to remove extensive anti-plasma protein activity. Following these procedures, sensitive techniques failed to reveal residual activity against alpha-macroglobulins, beta2-microglobulin and other human plasma proteins. The antiserum reacted with normal B lymphocytes but not with T lymphocytes or monocytes. Positive reactions were seen in B cell lymphomas, chronic lymphocytic leukaemia, hairy-cell leukaemia and uninucleated Reed-Sternberg cells.[Abstract] [Full Text] [Related] [New Search]