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  • Title: [Follow-up of Wegener's granulomatosis with kidney involvement].
    Author: Heinicke HJ.
    Journal: Z Urol Nephrol; 1986 Mar; 79(3):163-9. PubMed ID: 3716657.
    Abstract:
    It is reported on long-term courses in five patients with Wegener's granulomatosis. Under a treatment with glucocorticoids and immunosuppressive agents lasting several years in all cases a remission developed. In these cases the participation of the kidneys is fateful, whereby from the very beginning a large proportion of sclerosing glomeruli lead to a greater healing of the defect. While the troubles of the patients under the apparently at present unspecific effect of high doses of prednisolone disappear within a few weeks, the onset of the remission lasts at least nine months. It is tried to form criteria which indicate a remission. The treatment with a low maintenance dose for at least one year after the remission seems to be justified in consideration of the frequency of recidivations.
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