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  • Title: Characterization of an expanded subpopulation of large granular lymphocytes in a patient with rheumatoid arthritis.
    Author: Combe B, Andary M, Caraux J, Baldet P, Barchechath F, Clot J, Sany J.
    Journal: Arthritis Rheum; 1986 May; 29(5):675-9. PubMed ID: 3718558.
    Abstract:
    We describe a rheumatoid arthritis patient who was found to have chronic T cell lymphocytosis and neutropenia. She had an increased number of lymphocytes in the peripheral blood, bone marrow, and liver, and the expanded lymphocyte subset consisted of large granular lymphocytes with a homogeneous phenotype. Of the previously described patients with these large granular lymphocytes, almost one-fourth have had rheumatoid arthritis.
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