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  • Title: Paraneoplastic acrokeratosis: Bazex syndrome.
    Author: Boudoulas O, Camisa C.
    Journal: Cutis; 1986 Jun; 37(6):449-53. PubMed ID: 3720352.
    Abstract:
    Paraneoplastic acrokeratosis, or Bazex syndrome, is a rare, distinct dermatosis characterized by psoriasiform acral hyperkeratosis. In most cases, it is a specific cutaneous sign of an occult squamous cell carcinoma of the upper aerodigestive tract that has metastasized to cervical lymph nodes. We report the fifth American case of paraneoplastic acrokeratosis. The patient's skin disease was more remarkable for its hyperpigmentation than its hyperkeratosis. Nearly all of the hyperpigmentation resolved, but the nail dystrophy persisted seven months after the tumor had been treated using surgery and radiation.
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