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  • Title: On the role of K+ on succinic dehydrogenase activity.
    Author: Chávez E, Bravo C, Jay D.
    Journal: J Bioenerg Biomembr; 1986 Apr; 18(2):93-9. PubMed ID: 3722143.
    Abstract:
    The effect of potassium ions on succinic dehydrogenase activity of mitochondria was studied. The results showed that in these organelles K+ induces inhibition of the respiratory control; moreover, in submitochondrial particles potassium inhibits the rate of oxidation of succinate. The results showed also that K+ does not changes the Km for succinate but diminishes the Vmax. In addition, the data provide evidence that mitochondria oxidizing glutamate-malate in a sucrose medium show a higher activity of succinate dehydrogenase than mitochondria incubated in KCl.
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