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  • Title: Calcium transport in the endolymphatic sac.
    Author: Ninoyu O, Morgenstern C.
    Journal: ORL J Otorhinolaryngol Relat Spec; 1986; 48(4):199-202. PubMed ID: 3725335.
    Abstract:
    Ca++ activity and DC potential were measured in vivo in the endolymphatic sac (ES) of guinea pigs by means of double-barrelled ion-sensitive microelectrodes. We found a positive DC potential of 14 mV and a Ca++ activity of 4.7 X 10(-4) M. Anoxia induced a decrease in the DC potential and an increase in Ca++ activity; however, no negative DC potential was measured during permanent anoxia. The Ca++ activity measured was in agreement with the Ca++ value calculated with the Nernst equation, assuming a positive DC potential. On the basis of these data, it was suggested that the Ca++ in the ES is in electrochemical equilibrium with the surrounding fluid and no active Ca++ transport is necessary in the ES of guinea pigs.
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