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  • Title: Avascular necrosis of bone: a manifestation of Cushing's disease.
    Author: Phillips KA, Nance EP, Rodriguez RM, Kaye JJ.
    Journal: South Med J; 1986 Jul; 79(7):825-9. PubMed ID: 3726582.
    Abstract:
    Cushing's disease is endogenous hypercortisolism due to a pituitary adenoma. Although exogenous hypercortisolism is a well known cause of avascular necrosis and although there have been many reports of avascular necrosis associated with endogenous Cushing's syndrome, there has only been a single well documented case report associating avascular necrosis of bone with Cushing's disease. We report four new cases of avascular necrosis of bone in patients with well documented Cushing's disease.
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