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  • Title: Species Specificity of the Insect Prothoracicotropic Hormone (PITH): the Presence of Bombyx-and Samia-Specific PTTHs in the Brain of Bombyx mori: (prothoracicotropic hormone (PTTH)/peptide hormone species specificity/Bombyx mori/Samia Cynthia ricini).
    Author: Ishizaki H, Mizoguchi A, Fujishita M, Suzuki A, Moriya I, O'Oka H, Kataoka H, Isogai A, Nagasawa H, Tamura S, Suzuki A.
    Journal: Dev Growth Differ; 1983; 25(6):593-600. PubMed ID: 37281083.
    Abstract:
    Crude extracts of Bombyx mori brains can provoke adult development when injected into brain-removed dormant pupae of Bombyx mori and Samia Cynthia ricini. From this fact the prothoracicotropic hormone (PTTH) of Bombyx has long been thought to be species-nonspecifically active on Samia. Chemical fractionation of Bombyx brain or head extracts by fractional precipitation with acetone, Sephadex G-50 gel-filtration, and DEAE-Sepharose CL-6B chromatography, however, separated the fractions which activated Bombyx brainless pupae from those which activated Samia. Those results reveal the existence of two species-specific PTTHs.
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