These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Primary aldosteronism: changing concepts in diagnosis and management.
    Author: Lim RC, Nakayama DK, Biglieri EG, Schambelan M, Hunt TK.
    Journal: Am J Surg; 1986 Jul; 152(1):116-21. PubMed ID: 3728804.
    Abstract:
    Unilateral adrenalectomy for benign causes of primary aldosteronism is an established procedure. The established surgical cure for aldosterone-producing adenoma justifies a thorough preoperative evaluation. No single test accurately identifies aldosterone-producing adenomas in patients with primary aldosteronism. However, a useful algorithm combines postural studies, computerized axial tomography, and adrenal vein catheterization for selective hormonal assay, if computerized axial tomography is negative or equivocal and the suspicion of aldosterone-producing adenoma is high. If an adrenal mass is present and biochemical studies suggest a diagnosis of aldosterone-producing adenoma, resection of the affected gland from a limited unilateral approach is indicated. Cure can be expected in 80 percent of cases. In the uncommon circumstance that the adrenal tumor was not an aldosterone-producing adenoma but a hyperplastic nodule, these patients may still be cured or more easily controlled with antihypertensive medications. Thirty-eight patients who underwent unilateral adrenalectomy are presented and discussed.
    [Abstract] [Full Text] [Related] [New Search]