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Title: Freeze-fracture analysis of intramembrane particles of erythrocytes from normal and dystrophic hamsters. Author: Davis EC, Shivers RR. Journal: Anat Rec; 1986 Jun; 215(2):95-8. PubMed ID: 3729015. Abstract: The intramembrane particles on plasma membranes of erythrocytes of Syrian hamsters afflicted with hereditary muscular dystrophy were compared to those from normal controls by freeze-fracture analysis. The reduced number of particles in both fracture faces of dystrophic erythrocyte plasmalemmae, as compared to that of control red cells, was found to be highly significant (P = .001). Results of this study therefore, support the concept of a generalized membrane defect (abnormality) in muscular dystrophy.[Abstract] [Full Text] [Related] [New Search]