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  • Title: [Herbal-moxa plaster for diarrhea type irritable bowel syndrome of spleen and kidney yang deficiency: a randomized controlled trial].
    Author: Zhao ZR, Wang YX, Xu FY, Zhang WC, Wang QY, Huang W.
    Journal: Zhongguo Zhen Jiu; 2023 Jun 12; 43(6):617-21. PubMed ID: 37313553.
    Abstract:
    OBJECTIVE: To compare the clinical efficacy between herbal-moxa plaster and moxa-box moxibustion for diarrhea type irritable bowel syndrome (IBS-D) of spleen and kidney yang deficiency. METHODS: Eighty patients with IBS-D of spleen and kidney yang deficiency were randomly divided into a herbal-moxa plaster group and a moxa-box moxibustion group, 40 cases in each group. The patients in the two groups were treated with conventional acupuncture at Baihui (GV 20), Yintang (GV 24+), Zhongwan (CV 12) and bilateral Tianshu (ST 25), Yinlingquan (SP 9), and Taixi (KI 3), etc. In addition, the patients in the herbal-moxa plaster group were treated with herbal-moxa plaster (Wenyang Fuzheng ointment, composed of prepared monkshood, prepared evodia rutaecarpa, dried ginger, cinnamon, etc.) at Shenque (CV 8), Guanyuan (CV 4), Zhongwan (CV 12) and bilateral Tianshu (ST 25), Shenshu (BL 23) and Shangjuxu (ST 37); the patients in the moxa-box moxibustion group were treated with moxa-box moxibustion at the same acupoints as the herbal-moxa plaster group. The acupuncture-moxibustion treatment was provided once every other day for 4 weeks (14 treatments). Before and after treatment, the scores of clinical symptom of TCM, irritable bowel syndrome (IBS) symptom severity scale (IBS-SSS) and IBS quality of life scale (IBS-QOL) were compared between the two groups, and the clinical efficacy was evaluated. RESULTS: Compared with those before treatment, each item scores and total scores of clinical symptom of TCM, and IBS-SSS scores in the two groups were reduced after treatment (P<0.05). The abdominal bloating score, stool frequency score and total score of clinical symptom of TCM as well as IBS-SSS score in the herbal-moxa plaster group were lower than those in the moxa-box moxibustion group (P<0.05). Compared with those before treatment, the IBS-QOL scores in the two groups were increased after treatment (P<0.05), and the IBS-QOL score in the herbal-moxa plaster group was higher than that in the moxa-box moxibustion group (P<0.05). The total effective rate was 92.5% (37/40) in the herbal-moxa plaster group, which was higher than 85.0% (34/40) in the moxa-box moxibustion group (P<0.05). CONCLUSION: On the basis of conventional acupuncture treatment, herbal-moxa plaster could effectively improve the clinical symptoms and quality of life in IBS-D patients of spleen and kidney yang deficiency, and its efficacy is superior to that of moxa-box moxibustion. 目的:比较隔药灸贴与艾箱灸两种灸法治疗脾肾阳虚型腹泻型肠易激综合征(IBS-D)的临床疗效。方法:将80例脾肾阳虚型IBS-D患者随机分为隔药灸贴组和艾箱灸组,各40例。两组均予常规针刺治疗,穴取百会、印堂、中脘及双侧天枢、阴陵泉、太溪等。隔药灸贴组采用温阳扶正膏(制附片、制吴茱萸、干姜、肉桂等组成)在神阙、关元、中脘及双侧天枢、肾俞、上巨虚进行隔药灸贴,艾箱灸组在相同腧穴进行艾箱灸。针灸治疗均隔日1次,共治疗4周(14次)。比较两组患者治疗前后中医临床症状、肠易激综合征(IBS)严重程度量表(IBS-SSS)及IBS生活质量量表(IBS-QOL)评分,并评定临床疗效。结果:治疗后,两组患者中医临床症状各项评分及总分、IBS-SSS评分均较治疗前降低(P<0.05),隔药灸贴组患者中医临床症状评分中腹胀评分、大便次数评分、总分和IBS-SSS评分低于艾箱灸组(P<0.05);两组患者IBS-QOL评分较治疗前升高(P<0.05),且隔药灸贴组高于艾箱灸组(P<0.05)。隔药灸贴组总有效率为92.5%(37/40),高于艾箱灸组的85.0%(34/40,P<0.05)。结论:在常规针刺治疗基础上,隔药灸贴可有效改善脾肾阳虚型IBS-D患者临床症状及生活质量,疗效优于艾箱灸。.
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