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  • Title: [Cardiospecific enzyme activity and clinical significance of the parameters of blood enzymograms in the acute phase of myocardial infarction].
    Author: Makarovskiĭ VV, Sumarokov AV.
    Journal: Ter Arkh; 1986; 58(5):41-8. PubMed ID: 3738792.
    Abstract:
    Serial investigations of the activity of cardiospecific enzymes in the blood allowed one to reveal a prolonged type of a dynamic curve "enzymatic activity-time" characterized by two or more peaks in 66.7% of patients with the acute phase of myocardial infarction. It was assumed that such a curve type could be determined by the formation of multiple necrotic foci in the myocardium. A close correlation between the rate of increment and peak activity of the LDH, CPK and MB-CPK was shown. These and other parameters of the blood enzymogram in the acute phase of myocardial infarction made it possible to assess the development of a necrotic process in the myocardium and, consequently, a clinical course of disease.
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