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  • Title: In vivo effect of a high-cholesterol diet on the endothelial integrity of rat aorta.
    Author: Pellegreffi L, Branzoli U.
    Journal: Artery; 1986; 13(5):315-24. PubMed ID: 3741160.
    Abstract:
    A new technique for measuring spontaneous or induced endothelial lesions in animals was used to analyse the endothelial integrity of the aortas of rats fed a normolipidic or high-cholesterol diet. Animals fed a hypercholesterolic diet for 7 days differed from animals fed a normolipidic diet in that they presented endothelial lesions in accordance with the lipid hypothesis of atherosclerosis.
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