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  • Title: Effect of exogenous lipids incorporated into the membrane of human erythrocytes on its glucose transport activity.
    Author: Fujii T, Tamura A, Fujii H, Miwa I, Okuda J.
    Journal: Biochem Int; 1986 Jun; 12(6):873-9. PubMed ID: 3741447.
    Abstract:
    Addition of a phosphatidylcholine (dilinoleoyl), lysophosphatidylcholine (palmitoyl), saturated or unsaturated long-chain fatty acid (stearic or oleic) into human erythrocyte suspension caused both dose-dependent incorporation of the lipid into the membrane and inhibition of the glucose transport across the membrane. Loading to or partial removal of cholesterol from the membrane increased or decreased the transport rate, respectively. There was no correlation between the changes in the transport activity and those in cell shape caused by such alterations in the membrane lipid composition.
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