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  • Title: Additive interaction of aminophylline and salbutamol in asthma: an in vivo study using dose-response curves.
    Author: Leopold D, Handslip P.
    Journal: J Int Med Res; 1979; 7 Suppl 1():52-5. PubMed ID: 374165.
    Abstract:
    Dose-response curves to intravenous salbutamol were constructed after injection of saline or aminophylline in a group of ten asthmatic patients. The shape of the salbutamol dose-response curve was not altered by aminophylline pre-treatment--it is therefore argued that the drugs are additive but not synergistic on the basis of this preliminary study.
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