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  • Title: Experimental posterior perforating ocular injury: a controlled study of the gross effects of localised gamma irradiation.
    Author: Chakravarthy U, Maguire CJ, Archer DB.
    Journal: Br J Ophthalmol; 1986 Aug; 70(8):561-9. PubMed ID: 3741819.
    Abstract:
    A pilot study on the effect of localised irradiation applied to the site of a standard perforating injury in the rabbit eye, showed that gamma rays limited the formation of post-traumatic vitreoretinal membranes. A controlled study was therefore undertaken to confirm this observation. Twenty-four pairs of rabbits underwent a standard perforating injury in the right eye. One rabbit of each pair received a radioactive ophthalmic Cobalt applicator and the other a dummy applicator. Nineteen of 24 non-irradiated eyes developed vitreoretinal membranes, with associated traction retinal detachment. Only four of 24 irradiated eyes developed traction retinal detachment.
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