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  • Title: Surface modification of soft contact lenses: silanization, wettability and lysozyme adsorption studies.
    Author: Deng XM, Castillo EJ, Anderson JM.
    Journal: Biomaterials; 1986 Jul; 7(4):247-51. PubMed ID: 3741958.
    Abstract:
    The surface reactions of poly(2-hydroxyethylmethacrylate) (PHEMA) and the copolymer poly(HEMA-methacrylic acid) (PHEMA/MAA) with methyltrimethoxysilane, ethyltrimethoxysilane and phenyltrimethoxysilane have been characterized by attenuated total reflectance-Fourier transform infrared (ATR-FTIR) spectroscopy. A model compound, hydroxyethyl isobutyrate was synthesized and subsequently reacted with phenyltrimethoxysilane. Its FTIR spectrum was compared with the ATR-FTIR spectra mentioned above. Protein adsorption experiments showed that silanized PHEMA/MAA soft contact lenses adsorbed less lysozyme than the untreated lenses.
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