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  • Title: [Acute Renal Failure, Lactic Acidosis, and Metformin: Two Case Reports and Literature Review].
    Author: Faggian G, Cesaro A, Faggian R, Vitagliano A, Del Piano C, Del Piano D, Salzano M, Diglio A, Faggian A.
    Journal: G Ital Nefrol; 2023 Jun 29; 40(3):. PubMed ID: 37427902.
    Abstract:
    Lactic acidosis is a potential adverse event related to metformin therapy. Although metformin-associated lactic acidosis (MALA) is a rare condition (about 10 cases / 100,000 patients / year), new cases continue to be reported, with a mortality of 40-50%. We describe two clinical cases characterized by severe metabolic acidosis, hyperlactacidemia, and acute renal injury. The first also with NSTEMI, successfully treated.
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