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  • Title: [Acute normovolemic hemodilution in extensive surgical interventions].
    Author: von Bormann B, Weidler B, Boldt J, Jooss D, Aigner K, Peil J, Hempelmann G.
    Journal: Chirurg; 1986 Jul; 57(7):457-64. PubMed ID: 3743194.
    Abstract:
    In order to ascertain the effect of acute isovolaemic haemodilution on haemodynamics and various laboratory parameters as well as homologous blood consumption 44 patients undergoing major liver surgery were investigated in two groups: group I (n = 22) underwent acute normovolaemic haemodilution after induction of anaesthesia; group II (n = 22) had no blood withdrawn and served as control. Haemodilution led to typical haemodynamic effects such as increase in cardiac index and decrease in systemic as well as pulmonary vascular resistance; no detrimental effect of the procedure could be observed. Haemodilution led to a marked reduction in the consumption of banked blood which was on the average 1.8 units/patient against control intraoperatively and 3.1 units/patient postoperatively summing up to a total of 4.9 units/patient.
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