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  • Title: [Phenylethylamine fluorides. II. Synthesis and neurobiochemistry in the rat].
    Author: Charlon C, Luu-Duc C, Huguet F, Gérard P, Narcisse G.
    Journal: Farmaco Sci; 1986 Aug; 41(8):586-96. PubMed ID: 3743750.
    Abstract:
    Sixteen fluorinated phenylethylamines analogous to catecholamine were obtained by fluoration from the corresponding amino-alcohols. The biological activity of the compounds was evaluated by determining their affinity for the central adrenergic receptors of rat brain membranes and by measuring the monoamine synaptosomal uptake. These compounds significantly inhibited serotonine uptake, but they showed no affinity for amphetaminergic binding sites.
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