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  • Title: Rat liver microsomal phospholipase A2 and membrane fluidity.
    Author: Momchilova A, Petkova D, Koumanov K.
    Journal: Int J Biochem; 1986; 18(7):659-63. PubMed ID: 3743874.
    Abstract:
    The influence of the physical state and the lipid composition on microsomal membrane-bound phospholipase A2 activity has been investigated. It was established that the decrease of membrane fluidity expressed by the alterations of the steady-state fluorescent anisotropy (rs) and the structural order parameter for DPH (SDPH) leads to augmentation of phospholipase A2 specific activity. Phosphatidylinositol is the only phospholipid having a specific activating effect on microsomal membrane-bound phospholipase A2.
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