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Title: Frequency of the fragile X syndrome in Japanese mentally retarded males. Author: Arinami T, Kondo I, Nakajima S. Journal: Hum Genet; 1986 Aug; 73(4):309-12. PubMed ID: 3744362. Abstract: Among 243 institutionalized mentally retarded males in Japan, 13 patients (5.3%) with the fra(X)(q27) from nine families were detected. These 13 patients accounted for 8.6% of 152 male inmates with unknown causes of mental retardation in the population. One out of nine pedigrees had an apparently unaffected male transmitter of this disorder. Our data agree with the frequencies of the fra(X) syndrome in various retarded populations, most of which were Caucasians, suggesting that the prevalence of the fra(X) syndrome in Japanese is not significantly different from those in Caucasians.[Abstract] [Full Text] [Related] [New Search]