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  • Title: [Evaluation of ventilation using 133Xe for improved nuclear medicine lung diagnosis].
    Author: Schmidt HA, Michelsen E.
    Journal: Nuklearmedizin; 1986 Jun; 25(3):83-9. PubMed ID: 3748826.
    Abstract:
    In 101 patients a combined examination of ventilation with 133Xe and of perfusion with 99mTc-HAM was performed. By using the device 101 (Veenstra) the wash-in, equilibrium and wash-out could be evaluated in one examination, the total time needed for one patient was about 10 min. In suspected lung embolism the specificity could be increased to 100% whereas the sensitivity remained constant at 93%. In patients with central obstruction, specificity could be increased from 60% to 87% and sensitivity from 54% to 70%. In the diagnosis of lung embolism, the additional examination of ventilation should be used in any case, in the diagnosis of central obstruction it is recommended.
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