These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Antagonism of acute feeding response to 2-deoxyglucose and 5-thioglucose by GABA antagonists: the relative role of ventromedial and lateral hypothalamus.
    Author: Lenin Kamatchi G, Veeraragavan K, Chandra D, Bapna JS.
    Journal: Pharmacol Biochem Behav; 1986 Jul; 25(1):59-62. PubMed ID: 3749238.
    Abstract:
    The effect of GABA antagonists picrotoxin and bicuculline was studied on hyperphagia caused by 2-DG and 5-TG. The GABA antagonists were administered either SC or into the VMH or LH through stereotaxically implanted chronic cannulae. The peripheral as well as VMH injection antagonised the hyperphagia significantly. In contrast, injection of these agents into the LH failed to produce any effect. These findings show that in a glucoprivic state there might be an increased GABAergic activity in the VMH.
    [Abstract] [Full Text] [Related] [New Search]