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  • Title: Case report: New is not always better: treatment of non-bacterial thrombotic endocarditis.
    Author: Akiki E, Ahmad A, El-Am EA, Casanegra AI, Klarich KW, Kurmann R.
    Journal: Front Cardiovasc Med; 2023; 10():1208190. PubMed ID: 37502185.
    Abstract:
    An elderly female with metastatic adenocarcinoma of the lung and atrial fibrillation presented with multiple embolic strokes while on anticoagulation with Apixaban. After further investigation, a TEE showed lesions of non-bacterial thrombotic endocarditis on the mitral valve. A decision to switch the patient to LMWH for anticoagulation was then made and a follow-up TEE showed resolution of the NBTE. In this abstract, we show that heparin should remain as the anticoagulation agent of choice in the setting of NBTE associated with malignancy.
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