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  • Title: Mercapturic acid formation in the marmoset (Callithrix jacchus).
    Author: Hall BE, James SP.
    Journal: Xenobiotica; 1986 Jul; 16(7):609-14. PubMed ID: 3751115.
    Abstract:
    Benzylmercapturic acid is a major metabolite of [methylene-14C]benzyl chloride in the marmoset, as in the rat. The excretion of the minor metabolites benzylmercapturic acid sulphoxide and benzylcysteine accounted for a greater proportion of the dose than in the rat. Excretion of hippuric acid as a metabolite of benzyl chloride was variable in the marmoset. Acetylation of S-benzyl- and S-pentyl-L-cysteine to the corresponding mercapturic acids was extensive in the marmoset. Trace amounts of the sulphoxides of these acids were also excreted.
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