These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Intracellular potassium ion activity in resting and stimulated mouse pancreas and submandibular gland.
    Author: Poulsen JH, Oakley B.
    Journal: Proc R Soc Lond B Biol Sci; 1979 Mar 26; 204(1154):99-104. PubMed ID: 37516.
    Abstract:
    Intracellular potassium ion activities (aiK+) and membrane potentials were measured with double-barrelled, potassium-specific microelectrodes in superfused mouse pancreas and submandibular gland. Stimulation with the cholinergic agonist bethanechol caused a marked decrease in aiK+ in the submandibular gland, whereas no change in aiK+ could be detected in the pancreas. This indicates that bethanechol increases the permeability of the cell membranes to potassium ions in the submandibular gland but not in the pancreas. Pancreatic acinar cells hyperpolarized promptly when the extracellular potassium ion activity was restored after a prolonged period of potassium deprivation. In comparison, the recovery of aiK+ was a slow process. This finding gives support to the view that the hyperpolarization is due to electrogenic sodium pumping.
    [Abstract] [Full Text] [Related] [New Search]