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  • Title: [Effect of the delta-sleep peptide on parasympathetic regulation of the cardiac rhythm].
    Author: Zviagintseva MA, Kosharskaia IL, Ul'ianinskiĭ LS.
    Journal: Biull Eksp Biol Med; 1986 Apr; 101(4):390-1. PubMed ID: 3754472.
    Abstract:
    Effect of delta-sleep peptide (60 nM/kg) on the parasympathetic regulation of cardiac activity has been studied in the experiments on rabbits. It has been established that intravenous administration of this peptide to voluntary-behaving animals results in heart rate reduction by an average of 16%, that can be eliminated by atropine. Delta-sleep peptide has been demonstrated to intensify negative chronotropic effect in the case of directly irritated wandering nerve. The data obtained explain a protective effect of delta-sleep peptide on the heart under emotional stress.
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