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  • Title: Trivalvular nonbacterial thrombotic endocarditis in a patient with colon adenocarcinoma: a case report.
    Author: Bagheri A, Khani M, Akbari T, Ghadirzadeh E, Charkazi E, Ghorbani P.
    Journal: J Med Case Rep; 2023 Aug 07; 17(1):334. PubMed ID: 37545010.
    Abstract:
    BACKGROUND: Nonbacterial thrombotic endocarditis is a rare complication of prothrombotic states such as neoplasms that can cause valvular dysfunction and life-threatening complications. Nonbacterial thrombotic endocarditis usually affects the left-sided valves; however, only a minority of cases involving the tricuspid valve have been reported in medical literature. CASE PRESENTATION: The current report describes trivalvular involvement by nonbacterial thrombotic endocarditis in a 54-year-old Azeri female patient with metastatic colorectal carcinoma. This case underlines the necessity of evaluating nonbacterial thrombotic endocarditis as a possible consequence in cancer patients. When thromboembolic events are found in the presence of a hypercoagulable state (such as malignancy) and no growth on blood cultures, nonbacterial thrombotic endocarditis could be suspected as the cause. CONCLUSION: It is critical to achieve early diagnosis in such a setting to initiate treatment plans and prevent further complications rapidly.
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