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  • Title: An in vitro rat liver microsomal system for conjugating fatty acids to 11-hydroxy-delta 9-tetrahydrocannabinol.
    Author: Leighty EG.
    Journal: Res Commun Chem Pathol Pharmacol; 1979 Mar; 23(3):483-92. PubMed ID: 37559.
    Abstract:
    We have previously identified long-retained metabolites of delta 9-tetrahydrocannabinol (delta 9-THC) and delta 8-tetrahydrocannabinol (delta 8-THC) in the rat as fatty acid conjugates of 11-hydroxy-delta 9-THC and 11-hydroxy-delta 8-THC. These metabolites can be produced in vitro using a rat liver microsomal energy-dependent esterase system.
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