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  • Title: [Structural properties of leukemic and normal lymphoid cells].
    Author: Svirnovskiĭ AI, Tsygankov VG, Medved' IN, Shimanskaia TV, Levin VI.
    Journal: Biofizika; 1986; 31(4):638-42. PubMed ID: 3756231.
    Abstract:
    DNA synthesis intensity and spectral and fluorescent properties of leucemic, PHA-induced and intact normal mouse spleen cells and of nuclei isolated from these cells were investigated. The cell electrophoretic mobility and DNA-protein interaction in the nuclei were studied. Similarity in cell and nuclei fluorescence, fluorescence of the probe ANS conjugated with the cells, the electrophoretic mobility and tightness of DNA--protein interaction for leucemic and PHA--induced cells and also the similarity of the tightness of DNA--protein interaction for leucemic and normal intact cells were found inspite of the differences in DNA synthesis intensity and cell functional peculiarities.
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