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  • Title: [Effect of tyramine on the spinal cord afferent link of pressor reflexes].
    Author: Karagulova GO, Bochkina GI, Lukoshkova EV.
    Journal: Biull Eksp Biol Med; 1986 Sep; 102(9):266-8. PubMed ID: 3756319.
    Abstract:
    In anesthetized cats, tyramine application on the dorsal surface of C6-TI spinal cord segments suppressed the pressor components of blood pressure reflexes evoked by radial nerve A sigma or A + C afferent stimulation. Tyramine application on L4-SI spinal cord segments suppressed pressor reflexes to tibial nerve stimulation. Both the degree and the rate of reflex suppression increased with the rise in tyramine concentration from I to 4%. Along with these local effects "distant" tyramine action was demonstrated: pressor reflexes to radial nerve stimulation increased when tyramine was applied on L4-SI segments, but after its application on C6-TI segments pressor reflexes to tibial nerve stimulation increased in some cats, decreased in the other ones, or remained practically unchanged.
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