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  • Title: [Double blind clinical study of mianserin and nortriptyline (author's transl)].
    Author: Hoc J.
    Journal: Acta Psychiatr Belg; 1978; 78(5):833-40. PubMed ID: 375687.
    Abstract:
    The present study was done in double blind during 6 weeks on 36 depressed patients having a minimal score of 15 on the Hamilton rating scale. Seventeen received mianserin and nineteen nortriptyline. A comparable therapeutic efficacy was observed for both drugs, without significant differences for the delay of action or the activity during 6 weeks. The number of side-effects was much more elevated for nortriptyline, and a significant difference was particularly observed for the frequency and severity of tachycardia, dry mouth and oedema.
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