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  • Title: Sympathetic nervous system trophism for neuroblastoma and its age dependence in rats.
    Author: Chelmicka-Schorr E, Checinski ME, Jones KH, Yu RC, Arnason BG.
    Journal: Cancer Res; 1986 Nov; 46(11):5504-6. PubMed ID: 3756898.
    Abstract:
    The sympathetic nervous system modulates the growth of C-1300 mouse neuroblastoma in vivo and in vitro. We now report that a mitogenic/trophic factor that augments growth of C-1300 neuroblastoma and of the S-20 neuroblastoma clonal line is present in freshly excised sympathetic cervical ganglia from newborn rats, but is not detectable in homogenates from sympathetic ganglia obtained from adult rats.
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