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  • Title: Propionate metabolism and its regulation by fatty acids in ovine hepatocytes.
    Author: Faulkner A, Pollock HT.
    Journal: Comp Biochem Physiol B; 1986; 84(4):559-63. PubMed ID: 3757484.
    Abstract:
    Propionate metabolism was studied in ovine hepatocytes. The main products of metabolism were CO2, glucose, L-lactate and pyruvate. The fatty acids, butyrate and palmitate inhibited propionate oxidation; butyrate inhibited but palmitate slightly stimulated gluconeogenesis from propionate. Butyrate and palmitate also inhibited lactate and pyruvate production from both endogenous substrates and from propionate.
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