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Title: Herpes simplex virus gene therapy for dystrophic epidermolysis bullosa (DEB). Author: Epstein AL, Haag-Molkenteller C. Journal: Cell; 2023 Aug 17; 186(17):3523-3523.e1. PubMed ID: 37595560. Abstract: The FDA has recently approved Krystal biotech's beremagene geperpavec (B-VEC, Vyjuvek) to treat the wounds of dystrophic epidermolysis bullosa (DEB) patients. This represents a giant step, not only toward the treatment of this devastating disease, but also for the whole field of non-replicative (nr) recombinant HSV-1 vectors for gene therapy. To view this Bench to Bedside, open or download the PDF.[Abstract] [Full Text] [Related] [New Search]