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  • Title: Intensely potent anthracycline antibiotic oxaunomycin produced by a blocked mutant of the daunorubicin-producing microorganism.
    Author: Yoshimoto A, Fujii S, Johdo O, Kubo K, Ishikura T, Naganawa H, Sawa T, Takeuchi T, Umezawa H.
    Journal: J Antibiot (Tokyo); 1986 Jul; 39(7):902-9. PubMed ID: 3759649.
    Abstract:
    A new potent anthracycline antibiotic oxaunomycin was isolated from the culture broth of a blocked mutant derived from a baumycin producer and was identified as 7-O-(alpha-L-daunosaminyl)-beta-rhodomycinone. It exhibited about 100 times more strongly cytotoxic activity against leukemic L1210 cell culture than doxorubicin.
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