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  • Title: Antitumor agents, 79. Cytotoxic antileukemic alkaloids from Brucea antidysenterica.
    Author: Fukamiya N, Okano M, Aratani T, Negoro K, McPhail AT, Ju-ichi M, Lee KH.
    Journal: J Nat Prod; 1986; 49(3):428-34. PubMed ID: 3760882.
    Abstract:
    Two cytotoxic antileukemic alkaloids, the new 1,11-dimethoxycanthin-6-one (3) and the known 11-hydroxycanthin-6-one (1), as well as the known canthin-6-one (2) were isolated from the stem of Brucea antidysenterica. The structures of 1-3 were determined from their spectral data and X-ray analysis of the o-bromobenzoate of 1.
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