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  • Title: Chemical and pharmacological properties of some 7-beta-hydroxy-gamma-piperazinopropyl-8-benzylaminotheophylli nes.
    Author: Gorczyca M, Pawłowski M, Mrozikiewicz A, Kozłowska T, Wasik A.
    Journal: Pol J Pharmacol Pharm; 1986; 38(1):85-90. PubMed ID: 3763487.
    Abstract:
    In order to examine the circulatory and bronchospasmolytic activity, new 7-beta-hydroxy-gamma-N4-alkylpiperazinopropyl-8- benzylaminotheophyllines (1, 2, 3) were synthesized and converted to the water soluble dihydrochlorides (1a, 2a, 3a). They showed hypotensive and bronchodilatory effect.
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