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Pubmed for Handhelds

PUBMED FOR HANDHELDS

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  • Title: Myoadenylate deaminase deficiency: diagnosis by forearm ischemic exercise testing.
    Author: Valen PA, Nakayama DA, Veum JA, Wortmann RL.
    Journal: Adv Exp Med Biol; 1986; 195 Pt B():525-8. PubMed ID: 3766241.
    Abstract:
    These results indicate that measuring venous ammonia concentrations after forearm ischemic exercise is an effective means of screening for MADA deficiency but that submaximal exercise performance, whether due to weakness, pain or poor effort, can provide false positive results. Measurements of purine compounds released after exercise may increase the specificity of forearm ischemic exercise testing for MADA deficiency. The low level of purines released after exercise in MADA-deficient subjects supports the hypothesis that disordered purine metabolisms occurs when MADA activity is absent.
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