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  • Title: Effects of some neuroleptic drugs on aggressive behavior in isolated mice.
    Author: Rewerski W, Kostowski W, Piechocki T.
    Journal: Acta Physiol Pol; 1979; 30(2):295-8. PubMed ID: 37694.
    Abstract:
    Effects of some neuroleptic drugs on aggressive behavior in isolated mice. Acta Physiol. Pol. 1979, 30 (2): 295--298. Albino-Swiss male mice were isolated for 28 days and their isolation-induced aggressive behavior was tested after housing them in groups. The effects of the following neuroleptics were investigated: spiroperidol (0.2 mg/kg i.p.), pimozide (1 and 2 mg/kg i.p.), and clozapine (2 and 5 mg/kg i.p.). Among the drugs examined the strongest inhibitory action on the isolation-induced aggressive behavior was inserted by spiroperidol. Primozide and closapine had weaker, but significant anti-aggressive effect.
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