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  • Title: Severe hypoxemia after extubation secondary to myxedema coma: a case report.
    Author: Sun J, Peng Q, Huaguo Y, Hu L, Zhou H.
    Journal: J Int Med Res; 2023 Sep; 51(9):3000605231197947. PubMed ID: 37694899.
    Abstract:
    Myxedema coma is a rare and life-threatening endocrine emergency characterized by abnormalities in multiple organ systems. A 32-year-old woman with prolonged undiagnosed severe hypothyroidism was referred to our hospital owing to lower abdominal pain and menopause for more than 3 months. She underwent exploratory laparotomy and induced abortion under general anesthesia, and developed severe hypoxemia after extubation. She was diagnosed with myxedema coma, and was subsequently discharged with a good prognosis following treatment. This case suggests that myxedema coma should be considered a potential etiology of peri-operative hypoxemia. The findings in this case emphasize the importance of anesthesiologists' comprehensive understanding of myxedema coma. Prompt diagnosis followed by treatment is essential to reduce the mortality rate associated with this condition.
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