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  • Title: [Sex factor F of Escherichia coli K12 and its participation in mobilizing bacterial chromosomes].
    Author: Kaliaeva ES, Danilevskaia ON.
    Journal: Mol Biol (Mosk); 1977; 11(5):957-80. PubMed ID: 377055.
    Abstract:
    The structural and functional organization of F-factor reviewed and the physical map of F DNA, supplemented with a list of genetic markers, is presented. The DNA transfer during the conjugation is considered and especial attention is given to F-gene functions involved in this process. The special sequences of F DNA, homologous to resident insertion sequences in bacterial DNA are described and its participation in plasmido-chromosomal recombinant events both dependent and independent on recA function is discussed. The mechanism for chromosome mobilization by F-Factor are reviewed. A possibility of chromosome transfer without F DNA insertion is considered. In a latter case it proposed that spontaneous single-strand breaks may serve as the origins for initiation of chromosomal transfer.
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