These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: An extrinsic membrane polypeptide associated with high-molecular-weight protein aggregates in human cataract.
    Author: Spector A, Garner MH, Garner WH, Roy D, Farnsworth P, Shyne S.
    Journal: Science; 1979 Jun 22; 204(4399):1323-6. PubMed ID: 377484.
    Abstract:
    A 43,000-dalton polypeptide has been isolated from the high-molecular-weight disulfide-rich fraction of the water-insoluble protein of human cataractous lenses. On the basis of immunochemical reactivity and fluorescent antibody binding, this polypeptide is localized in the membrane region of the lens cell. This observation suggests an interaction between the soluble lens proteins and membrane-associated polypeptides in the formation of large protein aggregates which may cause cataract.
    [Abstract] [Full Text] [Related] [New Search]